Mytilene Lesvos North Aegean all tourist business is here. Food & Nightlife, Hotels, Rent a Cars, Rent a Yachts, Rooms to Let. Tours & Cruises, Transfers, Villas for Rent. Mytilene (Greek:Μυτιλήνη Mytilini) is a city founded in the 11th century BC. Mytilene is the capital and port of the island of Lesbos and also the capital of the North Aegean Region. The seat of the governor of the North Aegean Region is Mytilene. Mytilene is also one of 13 municipalities (counties) on the island of Lesbos. Mytilene is built on the southeast edge of the island. It is also the seat of a metropolitan bishop of the Orthodox church.

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